Why a topical Gel?

Carnosine taken orally is broken down in the body before much of it may be used. A topical Gel is designed for more efficient delivery by applying it through the skin.
The Gel uses patented transdermal delivery, with 41 patents worldwide. This describes the product design, not a guarantee of results.
The challenge with taking carnosine by mouth
Carnosine is a small molecule made from beta-alanine and L-histidine (see What is Carnosine). When it is swallowed, enzymes called carnosinases, found in the blood and other tissues, break much of it down quickly. Formulation research describes this rapid breakdown as a ceiling on how much carnosine taken orally may reach the tissues.
Beta-alanine loading and the tingle
Because of this breakdown, sport science has mostly focused on beta-alanine, the building block the body uses to make its own carnosine. Studies show it can raise muscle carnosine, but it usually takes daily doses over several weeks.
Beta-alanine is well known for causing a harmless tingling or pins-and-needles feeling on the skin (paresthesia), which some people find uncomfortable. That is one reason people look for other ways to support carnosine levels.
Delivering through the skin
The skin is designed to keep things out, especially water-based molecules like carnosine. Topical delivery research looks at ways to carry molecules across this barrier so they can bypass the digestive system.
Research on topical carnosine has explored areas such as the skin itself and eye drops for the lens, where reviews note that a topical approach was needed to reach the tissue. Researchers continue to study how well different delivery methods perform.
Patented delivery technology
The Gel my family uses a patented transdermal delivery system, protected by 41 patents worldwide. It is designed for more efficient delivery of carnosine through the skin compared with traditional oral approaches. The patents describe the product design, not a guarantee of results.
A Carnosine and Magnesium Gel
The Gel combines Carnosine and Magnesium in a water-based formula. Magnesium is a mineral involved in hundreds of processes in the body, including normal muscle function. Bringing the two together in a Gel means it can be applied where you want it, without capsules or loading phases.
How people use it
People generally apply a small amount of Gel to clean skin, often on areas such as the legs, shoulders or back, and rub it in until absorbed. Many make it part of their morning or evening routine, or apply it before or after activity. Follow the directions on the product, and remember everyone’s experience is different.
Want the research detail? Head to The Science.
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